Recombinant Human ZKSCAN3 Protein, Myc/DDK-tagged, C13 and N15-labeled ZKSCAN3-1789H

Specification Gene Information Related Products

Cat.No. :	ZKSCAN3-1789H
Product Overview :	ZKSCAN3 MS Standard C13 and N15-labeled recombinant protein (NP_077819) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migration in various tumors and myelomas.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	60.6 kDa
AA Sequence :	MARELSESTA LDAQSTEDQM ELLVIKVEEE EAGFPSSPDL GSEGSRERFR GFRYPEAAGP REALSRLREL CRQWLQPEMH SKEQILELLV LEQFLTILPG NLQSWVREQH PESGEEVVVL LEYLERQLDE PAPQVSGVDQ GQELLCCKMA LLTPAPGSQS SQFQLMKALL KHESVGSQPL QDRVLQVPML AHGGCCREDA VVASRLTPES QGLLKVEDVA LTLTPEWTQQ DSSQGNLCRD EKQENHGSLV SLGDEKQTKS RDLPPAEELP EKEHGKISCH LREDIAQIPT CAEAGEQEGR LQRKQKNATG GRRHICHECG KSFAQSSGLS KHRRIHTGEK PYECEECGKA FIGSSALVIH QRVHTGEKPY ECEECGKAFS HSSDLIKHQR THTGEKPYEC DDCGKTFSQS CSLLEHHRIH TGEKPYQCSM CGKAFRRSSH LLRHQRIHTG DKNVQEPEQG EAWKSRMESQ LENVETPMSY KCNECERSFT QNTGLIEHQK IHTGEKPYQC NACGKGFTRI SYLVQHQRSH VGKNILSQTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	ZKSCAN3 zinc finger with KRAB and SCAN domains 3 [ Homo sapiens (human) ]
Official Symbol :	ZKSCAN3
Synonyms :	ZKSCAN3; zinc finger with KRAB and SCAN domains 3; zinc finger protein 306, zinc finger protein 309, ZNF306, ZNF309; zinc finger protein with KRAB and SCAN domains 3; dJ874C20.1; ZF47; Zfp47; zinc finger protein 306; zinc finger protein 309; zinc finger protein zfp47; zinc finger protein 47 homolog; zinc finger and SCAN domain-containing protein 13; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; dJ874C20.1.; FLJ33906; KIAA0426;
Gene ID :	80317
mRNA Refseq :	NM_024493
Protein Refseq :	NP_077819
MIM :	612791
UniProt ID :	Q9BRR0