Recombinant Human ZNF281 Protein, His-tagged

• Cat.No.: ZNF281-139H
• Product Overview: Recombinant Human ZNF281 Protein, fused to His-tag, was expressed in E. coli.

Specification

• Description: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of gene expression; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription, DNA-templated. Located in nucleoplasm.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Supplied as a 0.2 μm filtered solution in 30mM Tris，300 mM NaCl , pH8.0.
• Molecular Mass: ~99 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMKIGS GFLSGGGGTGSSGGSGSGGGGSGGG GGGGSSGRRAEMEPTFPQGMVMFNH RLPPVTSFTRPAGSAAPPPQCVLSS STSAAPAAEPPPPPAPDMTFKKEPA ASAAAFPSQRTSWGFLQSLVSIKQE KPADPEEQQSHHHHHHHHYGGLFAG AEERSPGLGGGEGGSHGVIQDLSIL HQHVQQQPAQHHRDVLLSSSSRTDD HHGTEEPKQDTNVKKAKRPKPESQG IKAKRKPSASSKPSLVGDGEGAILS PSQKPHICDHCSAAFRSSYHLRRHV LIHTGERPFQCSQCSMGFIQKYLLQ RHEKIHSREKPFGCDQCSMKFIQKY HMERHKRTHSGEKPYKCDTCQQYFS RTDRLLKHRRTCGEVIVKGATSAEP GSSNHTNMGNLAVLSQGNTSSSRRK TKSKSIAIENKEQKTGKTNESQISN NINMQSYSVEMPTVSSSGGIIGTGI DELQKRVPKLIFKKGSRKNTDKNYL NFVSPLPDIVGQKSLSGKPSGSLGI VSNNSVETIGLLQSTSGKQGQISSN YDDAMQFSKKRRYLPTASSNSAFSI NVGHMVSQQSVIQSAGVSVLDNEAP LSLIDSSALNAEIKSCHDKSGIPDE VLQSILDQYSNKSESQKEDPFNIAE PRVDLHTSGEHSELVQEENLSPGTQ TPSNDKASMLQEYSKYLQQAFEKST NASFTLGHGFQFVSLSSPLHNHTLF PEKQIYTTSPLECGFGQSVTSVLPD SLPKPPFGMLFGSQPGLYLSALDAT HQQLTPSQELDDLIDSQKNLETSSA FQSSSQKLTSQKEQKNLESSTGFQI PSQELASQIDPQKDIEPRTTYQIEN FAQAFGSQFKSGSRVPMTFITNSNG EVDHRVRTSVSDFSGYTNMMSDVSE PCSTRVKTPTSQSYR
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.17 mg/ml

Gene Information

• Gene Name: ZNF281 zinc finger protein 281 [ Homo sapiens (human) ]
• Official Symbol: ZNF281
• Synonyms: GZP1; ZBP99; ZBP-99; ZNP-99
• Gene ID: 23528
• mRNA Refseq: NM_001281293
• Protein Refseq: NP_001268222
• MIM: 618703
• UniProt ID: Q9Y2X9