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Recombinant Human ZYX Protein, Myc/DDK-tagged, C13 and N15-labeled
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| Cat.No. : | ZYX-3269H |
| Product Overview : | ZYX MS Standard C13 and N15-labeled recombinant protein (NP_001010972) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
| Description : | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc/DDK |
| Molecular Mass : | 61.3 kDa |
| AA Sequence : | MAAPRPSPAI SVSVSAPAFY APQKKFGPVV APKPKVNPFR PGDSEPPPAP GAQRAQMGRV GEIPPPPPED FPLPPPPLAG DGDDAEGALG GAFPPPPPPI EESFPPAPLE EEIFPSPPPP PEEEGGPEAP IPPPPQPREK VSSIDLEIDS LSSLLDDMTK NDPFKARVSS GYVPPPVATP FSSKSSTKPA AGGTAPLPPW KSPSSSQPLP QVPAPAQSQT QFHVQPQPQP KPQVQLHVQS QTQPVSLANT QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE ALSAGTGSPQ PPSFTYAQQR EKPRVQEKQH PVPPPAQNQN QVRSPGAPGP LTLKEVEELE QLTQQLMQDM EHPQRQNVAV NELCGRCHQP LARAQPAVRA LGQLFHIACF TCHQCAQQLQ GQQFYSLEGA PYCEGCYTDT LEKCNTCGEP ITDRMLRATG KAYHPHCFTC VVCARPLEGT SFIVDQANRP HCVPDYHKQY APRCSVCSEP IMPEPGRDET VRVVALDKNF HMKCYKCEDC GKPLSIEADD NGCFPLDGHV LCRKCHTARA QTTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : | 50 μg/mL as determined by BCA |
| Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
| SDS-PAGE : |
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| Gene Name : | ZYX zyxin [ Homo sapiens (human) ] |
| Official Symbol : | ZYX |
| Synonyms : | ZYX; zyxin; zyxin-2; ESP-2; HED-2; |
| Gene ID : | 7791 |
| mRNA Refseq : | NM_001010972 |
| Protein Refseq : | NP_001010972 |
| MIM : | 602002 |
| UniProt ID : | Q15942 |
◆ Recombinant Protein
| ZYX-1056H | Recombinant Human ZYX Protein, His-tagged | +Inquiry |
| Zyx-7135M | Recombinant Mouse Zyx Protein, Myc/DDK-tagged | +Inquiry |
| ZYX-433H | Recombinant Human ZYX Protein, His-tagged | +Inquiry |
| ZYX-1205C | Recombinant Chicken ZYX | +Inquiry |
| ZYX-19263M | Recombinant Mouse ZYX Protein | +Inquiry |
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◆ Lysates
| ZYX-9178HCL | Recombinant Human ZYX 293 Cell Lysate | +Inquiry |
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