Recombinant Monkey CD160 Protein, His-tagged, Alexa Fluor 488 conjugated

• Cat.No.: CD160-314RAF488
• Product Overview: Alexa Fluor 488 conjugated recombinant Rhesus CD160 (XP_001089019.1) (Met1-Leu158) was expressed with a polyhistidine tag at the C-terminus.

Specification

• Species: Monkey
• Source: HEK293
• Tag: His
• Protein Length: Met1-Leu158, 145
• Description: CD160 antigen, also known as Natural killer cell receptor BY55 and CD160, is a cell membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD160 is a GPI-anchored lymph centigradeyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim)CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 is expressed in spleen, peripheral blood, and small intestine. Expression of CD160 is restricted to functional NK and T cytotoxic lymph centigradeytes. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. Unique CD4+ CD160+ lymph centigradeyte subset may play a role in the pathogenesis of skin inflammation. Activated NK lymph centigradeytes release a soluble form of CD160 that functionally impairs the MHC-I-specific cytotoxic CD8(+) T lymph centigradeyte responsiveness.
• Form: Lyophilized
• Molecular Mass: 16.3 kDa
• N-terminal Sequence Analysis: Gly 25
• Endotoxin: < 1.0 EU/ μg of the protein as determined by the LAL method.
• Purity: (70+22.5) % as determined by SDS-PAGE
• Characteristic: Disulfide-linked homodimer
  Labeled with Alexa Fluor 488 via amines
  Excitation Wavelength: 488 nm
  Emission Wavelength: 515­-545 nm
• Storage: Samples are stable for up to twelve months from date of receipt at -70 centigrade. Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
• Conjugation: Alexa Fluor 488

Gene Information

• Gene Name: CD160 CD160 molecule [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: CD160
• Synonyms: CD160; CD160 molecule; CD160 antigen
• Gene ID: 696832
• mRNA Refseq: XM_015150329
• Protein Refseq: XP_015005815