Recombinant Mouse Acadvl Protein, MYC/DDK-tagged

• Cat.No.: Acadvl-504M
• Product Overview: Purified recombinant protein of full-length mouse acyl-Coenzyme A dehydrogenase, very long chain (Acadvl), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a homodimeric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-double bond in a FAD-dependent reaction. As beta-oxidation cycles through its four steps, each member of the acyl-CoA dehydrogenase family works at an optimum fatty acid chain-length. This enzyme has its optimum length between C16- and C20-acylCoA and localizes to the inner mitochondrial membrane (unlike related acyl-CoA dehydrogenases). In mice, deficiency of this gene can cause ventricular arrhythmias as well as fasting and cold intolerance.
• Molecular Mass: 70.9 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Acadvl acyl-Coenzyme A dehydrogenase, very long chain [ Mus musculus (house mouse) ]
• Official Symbol: Acadvl
• Synonyms: Acadvl; acyl-Coenzyme A dehydrogenase, very long chain; vlcad; very long-chain specific acyl-CoA dehydrogenase, mitochondrial; MVLCAD;
  EC 1.3.8.9
• Gene ID: 11370
• mRNA Refseq: NM_017366
• Protein Refseq: NP_059062
• UniProt ID: P50544