Recombinant Mouse Acp2 Protein, MYC/DDK-tagged

• Cat.No.: Acp2-515M
• Product Overview: Purified recombinant protein of full-length mouse acid phosphatase 2, lysosomal (Acp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Two isoforms are predicted to be produced from the same mRNA by the use of alternative in-frame translation termination codons via a stop codon readthrough mechanism.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 48.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Acp2 acid phosphatase 2, lysosomal [ Mus musculus (house mouse) ]
• Official Symbol: Acp2
• Synonyms: Acp2; acid phosphatase 2, lysosomal; LAP; Acp-2; lysosomal acid phosphatase; EC 3.1.3.2
• Gene ID: 11432
• mRNA Refseq: NM_007387
• Protein Refseq: NP_031413
• UniProt ID: P24638