Recombinant Mouse Adsl Protein, MYC/DDK-tagged

• Cat.No.: Adsl-549M
• Product Overview: Purified recombinant protein of full-length mouse adenylosuccinate lyase (Adsl), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a protein that is involved in adenosine monophosphate (AMP) biosynthesis and maintaining AMP levels in the muscle. The encoded enzyme catalyzes the release of fumarate during AMP biosynthesis by cleaving the substrates succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide (AICA) ribotide, and adenylosuccinate to give adenylate. In humans, this gene is associated with adenylosuccinate deficiency, a rare autosomal disorder resulting in a spectrum of neurological symptoms. A pseudogene associated with this gene is located on the X chromosome.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 54.9 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Adsl adenylosuccinate lyase [ Mus musculus (house mouse) ]
• Official Symbol: Adsl
• Synonyms: Adsl; adenylosuccinate lyase; Adl; Asl; adenylosuccinate lyase; ASase; adenylosuccinase; adenylosuccinate lyase 1; EC 4.3.2.2
• Gene ID: 11564
• mRNA Refseq: NM_009634
• Protein Refseq: NP_033764
• UniProt ID: P54822