Recombinant Mouse Alas2 Protein, His-tagged

• Cat.No.: Alas2-113M
• Product Overview: Recombinant Mouse Alas2 Protein (Ala361-Ala587) with N-His tag was expressed in E. coli.

Specification

• Description: Enables 5-aminolevulinate synthase activity. Involved in erythrocyte differentiation; heme biosynthetic process; and hemoglobin biosynthetic process. Acts upstream of or within cellular iron ion homeostasis. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in cutaneous porphyria; erythropoietic protoporphyria; hemochromatosis; sideroblastic anemia; and sideroblastic anemia 1. Orthologous to human ALAS2 (5'-aminolevulinate synthase 2).
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.7 kDa
  Accurate Molecular Mass: 29 kDa
• Protein length: Ala361-Ala587
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Alas2 aminolevulinic acid synthase 2, erythroid [ Mus musculus (house mouse) ]
• Official Symbol: Alas2
• Synonyms: ALAS2; aminolevulinic acid synthase 2, erythroid; 5-aminolevulinate synthase, erythroid-specific, mitochondrial; delta-ALA synthase 2; erythroid-specific ALAS; 5-aminolevulinic acid synthase 2; delta-aminolevulinate synthase 2; ALAS; ALASE; ALAS-E; Alas-2
• Gene ID: 11656
• mRNA Refseq: NM_001102446
• Protein Refseq: NP_001095916
• UniProt ID: P08680