Recombinant Mouse ALDH18A1 Protein

• Cat.No.: ALDH18A1-1517M
• Product Overview: Recombinant Mouse ALDH18A1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Aldh18a1 aldehyde dehydrogenase 18 family, member A1 [ Mus musculus ]
• Official Symbol: ALDH18A1
• Gene ID: 56454
• mRNA Refseq: NM_019698.2
• Protein Refseq: NP_062672.2
• UniProt ID: Q9Z110

Reviews

01/15/2022

Its speed in modulating signaling pathways allowed us to obtain results quickly, saving valuable time.

03/14/2017

The product's ability to accelerate research progress made it invaluable for time-critical projects.

10/02/2016

Time-sensitive assays were notably improved by the swift effects of the product.

Q&As

What is the primary function of ALDH18A1?

ALDH18A1 encodes delta-1-pyrroline-5-carboxylate synthetase, an enzyme involved in proline biosynthesis.

Is ALDH18A1 associated with amino acid metabolism?

Yes, ALDH18A1 is associated with amino acid metabolism, specifically in the synthesis of the amino acid proline.

How does ALDH18A1 contribute to cellular homeostasis?

ALDH18A1 contributes to cellular homeostasis by regulating the production of proline, an amino acid with various cellular functions.

Are there diseases associated with ALDH18A1 dysfunction?

Mutations in ALDH18A1 can lead to a rare genetic disorder called type I hyperprolinemia, characterized by elevated levels of proline in the blood.

In what cellular processes does ALDH18A1 play a role?

ALDH18A1 participates in the conversion of glutamate to pyrroline-5-carboxylate, a crucial step in proline biosynthesis.

Can ALDH18A1 be targeted for therapeutic interventions?

Therapeutic interventions targeting ALDH18A1 may be explored for conditions related to proline metabolism, but this would require careful consideration due to the essential role of proline in various cellular processes.

What is the subcellular location of ALDH18A1?

ALDH18A1 is typically located in the mitochondria, where it carries out the biosynthesis of proline.