Recombinant Mouse Aldh6a1 Protein, MYC/DDK-tagged Aldh6a1-267M

Recombinant Mouse Aldh6a1 Protein, MYC/DDK-tagged


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Recombinant Mouse Aldh6a1 Protein, MYC/DDK-tagged

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Cat.No. : Aldh6a1-267M
Product Overview : Purified recombinant protein of full-length mouse aldehyde dehydrogenase family 6, subfamily A1 (Aldh6a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded enzyme is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This enzyme catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Mutations in the human gene result in Methylmalonate Semialdehyde Dehydrogenase Deficiency, characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants encoding different isoforms.
Source : HEK293T
Species : Mouse
Molecular Mass : 58 kDa
Purity : >80%, as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Aldh6a1 aldehyde dehydrogenase family 6, subfamily A1 [ Mus musculus (house mouse) ]
Official Symbol : Aldh6a1
Synonyms : Aldh6a1; aldehyde dehydrogenase family 6, subfamily A1; Mmsdh; 1110038I05Rik; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; aldehyde dehydrogenase family 6 member A1; malonate-semialdehyde dehydrogenase; EC; EC
Gene ID : 104776
mRNA Refseq : NM_134042
Protein Refseq : NP_598803
UniProt ID : Q9EQ20

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