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Recombinant Mouse Alg1 Protein, Myc/DDK-tagged

Cat.No. : Alg1-1597M
Product Overview : Purified recombinant protein of mouse full-length asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase) (Alg1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc2-Man5 intermediate on the cytoplasmic surface of the ER.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 54.9 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Alg1 asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase) [ Mus musculus (house mouse) ]
Official Symbol : Alg1
Synonyms : ALG1; asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase); chitobiosyldiphosphodolichol beta-mannosyltransferase; beta-1,4 mannosyltransferase; beta-1,4-mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; asparagine-linked glycosylation protein 1 homolog; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; HMT1; HMAT1; MGC18946
Gene ID : 208211
mRNA Refseq : NM_145362
Protein Refseq : NP_663337
UniProt ID : Q921Q3

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (19)

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What is the ALG1 test fee? 10/20/2022

ALG1 testing costs vary by hospital and region and may fluctuate within a range.

Does ALG1 detection require special preparation and precautions? 09/29/2022

ALG1 testing does not require special preparation before it is performed, but if a blood sample needs to be collected, the blood collection process needs to be completed under the guidance of a doctor.

What groups of people are more susceptible to ALG1 defects? 05/25/2022

ALG1 deficiency is a genetic disorder, so it may affect members of its family.

How is ALG1 defect caused? 03/23/2022

ALG1 defects are usually caused by mutations, loss or deletion of genes, which in turn affect the metabolism of protein glycosylation.

Does ALG1 defect affect fertility? 01/14/2022

ALG1 defects may affect fertility and can cause problems such as genetic disorders.

What is the role of ALG1 in the human body? 11/04/2021

ALG1 is an important gene involved in protein glycosylation in human body, and plays an important role in maintaining the normal function of human body.

Is ALG1 testing routine? 10/14/2021

Testing is not a routine procedure and is usually done on the advice of a doctor.

What factors interfere with ALG1 detection? 08/14/2021

Detection can be interfered with by a number of factors, such as clinical symptoms, age, gender, diet, and so on.

Is there a familial risk of ALG1 deficiency? 02/11/2021

Deficiency has a familial genetic risk, and the risk of developing the disease depends on the family genetic history.

How to interpret the test results of ALG1? 07/14/2020

ALG1 test results need to be interpreted and analyzed by a professional.

Does the ALG1 test require a professional? 04/28/2020

ALG1 testing is performed by a professional clinical geneticist and laboratory technician.

What diseases is the ALG1 test mainly used to detect? 04/13/2020

ALG1 detection is mainly used to detect CDG1K and other related diseases.

Can ALG1 defects be inherited? 03/23/2020

ALG1 deficiency is a genetic disorder that can be passed on to future generations through genes.

What Clinical application ALG1 tested for? 03/02/2020

This protein can be tested in the form of blood or oral swabs.

Does ALG1 test require fasting? 02/02/2020

Testing does not require fasting.

What diseases can ALG1 defect cause? 01/17/2020

Deficiency of ALG1 may cause a rare glycoprotein Disorder called Glycosylation 1k syndrome (CDG1K), which includes mental retardation, motor degeneration, and muscle relaxation.

What are the symptoms of ALG1 defect? 12/30/2019

Deficiency may cause mental retardation, motor function degradation, fluid on the head, eye problems and other symptoms.

How is ALG1 defect treated? 11/22/2019

Deficiency can be treated with targeted treatment for its clinical manifestations, such as symptom relief, rehabilitation, etc.

Can ALG1 test protect against disease? 07/15/2019

Testing may help in the early detection of related diseases, so that targeted prevention and treatment measures can be taken, but often cannot prevent all related diseases.

Customer Reviews (4)

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Reviews
02/24/2022

    The protein specificity is high and the misdiagnosis rate is low.

    12/22/2020

      The most suitable detection method is ELISA.

      12/15/2020

        High sensitivity in diagnosis.

        04/13/2020

          Detection limit is low, low content can also be successfully detected。

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