Recombinant Mouse Amd1 Protein, MYC/DDK-tagged
Cat.No. : | Amd1-591M |
Product Overview : | Purified recombinant protein of full-length mouse S-adenosylmethionine decarboxylase 1 (Amd1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Broad expression in bladder adult (RPKM 38.2), liver E14 (RPKM 34.2) and 24 other tissues. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 38.3 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Amd1 S-adenosylmethionine decarboxylase 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Amd1 |
Synonyms : | Amd1; S-adenosylmethionine decarboxylase 1; Amd-1; SAMDC; SAMDC 1; AdoMetDC; adoMetDC1; S-adenosylmethionine decarboxylase proenzyme 1; adoMetDC 1; EC 4.1.1.50 |
Gene ID : | 11702 |
mRNA Refseq : | NM_009665 |
Protein Refseq : | NP_033795 |
UniProt ID : | P0DMN7 |
Products Types
◆ Recombinant Protein | ||
AMD1-130H | Recombinant Human AMD1 Protein, His-tagged | +Inquiry |
AMD1-303R | Recombinant Rat AMD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
AMD1-1941C | Recombinant Chicken AMD1 | +Inquiry |
AMD1-9610H | Recombinant Human AMD1, GST-tagged | +Inquiry |
AMD1-647R | Recombinant Rat AMD1 Protein | +Inquiry |
◆ Lysates | ||
AMD1-8886HCL | Recombinant Human AMD1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAMD1 interacts with other enzymes, such as ornithine decarboxylase (ODC) and S-adenosylmethionine decarboxylase (SAMDC), in the polyamine biosynthetic pathway, forming a regulatory network.
Alterations in AMD1 expression or activity have been observed in various diseases, including cancer, suggesting its potential as a diagnostic marker or therapeutic target for specific conditions.
AMD1 expression is regulated at the transcriptional level by various factors, including growth factors, hormones, and cellular stressors.
AMD1 represents a potential pharmacological target for modulating polyamine metabolism, and its inhibition has been explored as a therapeutic strategy in diseases such as cancer.
AMD1 deficiency or inhibition can lead to altered polyamine levels and impaired cellular processes, including reduced cell proliferation and compromised cell survival.
AMD1 plays a key role in polyamine biosynthesis, regulating the levels of polyamines such as putrescine, spermidine, and spermine, which are involved in cell growth, proliferation, and differentiation.
AMD1 is an enzyme that catalyzes the conversion of S-adenosylmethionine (SAM) to decarboxylated SAM, which is a crucial step in the biosynthesis of polyamines.
The catalytic activity and substrate specificity of AMD1 are determined by its unique protein structure, including active site residues and cofactor binding sites.
AMD1 activity influences downstream signaling pathways, including mTOR signaling, DNA methylation, and gene expression, which are involved in cell growth and proliferation.
The substrates of AMD1 include SAM, the primary methyl donor in cellular methylation reactions, and its decarboxylated product, which serves as a precursor for polyamine synthesis.
Customer Reviews (3)
Write a reviewCompatibility with high-resolution imaging techniques for detailed analysis.
Accurate measurement of protein turnover rates.
Reduced non-specific binding in antibody-based assays.
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