Recombinant Mouse Apip Protein, Myc/DDK-tagged

• Cat.No.: Apip-1660M
• Product Overview: Purified recombinant protein of mouse full-length APAF1 interacting protein (Apip), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 26.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Apip APAF1 interacting protein [ Mus musculus (house mouse) ]
• Official Symbol: Apip
• Synonyms: APIP; APAF1 interacting protein; probable methylthioribulose-1-phosphate dehydratase; MTRu-1-P dehydratase; monocyte macrophage 19; APAF1-interacting protein; monocyte/macrophage protein 19; APIP2; CGI-29; Mmrp19
• Gene ID: 56369
• mRNA Refseq: NM_019735
• Protein Refseq: NP_062709
• UniProt ID: Q9WVQ5