Recombinant Mouse Apoc3 Protein, MYC/DDK-tagged

• Cat.No.: Apoc3-818M
• Product Overview: Purified recombinant protein of full-length mouse apolipoprotein C-III (Apoc3), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: This gene encodes an apolipoprotein which is the major protein component of very-low-density lipoproteins (VLDL) and a minor component of high-density lipoproteins (HDL). The encoded protein is thought to regulate the metabolism of triglyceride-rich lipoproteins and play a role in lipid storage and the mobilization of fat cells. This gene is clustered with three other apolipoprotein genes on chromosome 9 and is associated with coronary disease. Mice lacking this gene have lower levels of total cholesterol in the plasma. Mutations in the human genes causes hyperalphalipoproteinemia 2, a disorder of lipid metabolism which results in a favorable lipid profile (lower LDL-cholesterol, higher HDL-cholesterol and lower levels of serum triglycerides when fasting and after a meal). Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 11.4 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Apoc3 apolipoprotein C-III [ Mus musculus (house mouse) ]
• Official Symbol: Apoc3
• Synonyms: Apoc3; apolipoprotein C-III; apo-CIII; apoC-III; apolipoprotein C-III; apolipoprotein C3
• Gene ID: 11814
• mRNA Refseq: NM_023114
• Protein Refseq: NP_075603
• UniProt ID: P33622