Recombinant Mouse Arfrp1 Protein, Myc/DDK-tagged

• Cat.No.: Arfrp1-1677M
• Product Overview: Purified recombinant protein of mouse full-length ADP-ribosylation factor related protein 1 (cDNA clone MGC:61235 IMAGE:5720540), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The gene encodes a membrane-associated GTPase that is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. It plays an essential role in Golgi function controlling recruitment of GRIP domain proteins and ARL1 to the trans-Golgi and trans-Golgi to plasma membrane trafficking of cell surface proteins such as E-cadherin. Deletion of this gene in mice leads to embryonic lethality during early gastrulation, which is at least partly caused by the disruption of E-cadherin trafficking to the cell surface and therefore lack of sufficient cell-cell adhesion in the embryo. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 13.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arfrp1 ADP-ribosylation factor related protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Arfrp1
• Synonyms: Arfrp1; ADP-ribosylation factor related protein 1; AI480700; 1500006I01Rik; ADP-ribosylation factor-related protein 1; ARF-related protein 1; EC 3.6.5.1; EC 3.6.5.2; EC 3.6.5.3; EC 3.6.5.4
• Gene ID: 76688
• mRNA Refseq: NM_029702
• Protein Refseq: NP_083978
• UniProt ID: Q8BXL7