Recombinant Mouse Arntl Protein, MYC/DDK-tagged

• Cat.No.: Arntl-650M
• Product Overview: Purified recombinant protein of full-length mouse aryl hydrocarbon receptor nuclear translocator-like (Arntl), transcript variant 1, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 68.7 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arntl aryl hydrocarbon receptor nuclear translocator-like [ Mus musculus (house mouse) ]
• Official Symbol: Arntl
• Synonyms: Arntl; aryl hydrocarbon receptor nuclear translocator-like; MOP3; Arnt3; Bmal1; BMAL1b; bHLHe5; bmal1b'; aryl hydrocarbon receptor nuclear translocator-like protein 1; brain and muscle ARNT-like 1
• Gene ID: 11865
• mRNA Refseq: NM_007489
• Protein Refseq: NP_031515
• UniProt ID: Q9WTL8