Recombinant Mouse ARPM1 Protein, His (Fc)-Avi-tagged

• Cat.No.: ARPM1-752M
• Product Overview: Recombinant Mouse ARPM1 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Mouse
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Arpm1 actin related protein M1 [ Mus musculus ]
• Official Symbol: ARPM1
• Gene ID: 76652
• mRNA Refseq: NM_029690.2
• Protein Refseq: NP_083966.1
• UniProt ID: Q8BXF8

Reviews

11/20/2022

The ARPM1 protein stands out as a protein of exceptional quality, perfectly suited to meet the experimental needs of researchers.

04/21/2020

Whether utilized in protein-protein interaction studies or enzymatic assays, this protein exhibits robust performance, enabling accurate data generation and analysis.

09/01/2017

With its reliable performance and consistent results, the ARPM1 protein provides researchers with the confidence and accuracy required for successful experimentation.

Q&As

Is ARPM1 protein regulated by any post-translational modifications?

The specific post-translational modifications of ARPM1 are not well-studied. However, like other proteins in the Arp2/3 complex, it is likely that ARPM1 can undergo modifications such as phosphorylation, acetylation, or ubiquitination to regulate its function.

Does ARPM1 protein have any unique structural features?

ARPM1 protein contains structural domains similar to other subunits of the Arp2/3 complex. It has an alpha-helical domain that interacts with other subunits and an extended ARM/HEAT repeat domain involved in protein-protein interactions and actin binding.

Can ARPM1 protein be used as a diagnostic or prognostic marker for any diseases?

At present, ARPM1 protein has not been established as a clinically useful diagnostic or prognostic marker for any specific diseases. However, further research might uncover its potential utility in disease diagnosis or prognosis.

Is ARPM1 protein involved in any diseases?

Limited studies have linked dysregulation of the Arp2/3 complex, including ARPM1, with certain diseases such as cancer, neurological disorders, and autoimmune diseases. However, more research is needed to understand its specific roles in disease progression.

Are there any known genetic variations or mutations in the ARPM1 gene?

While specific variations or mutations in the ARPM1 gene have not been extensively studied, genetic variations in other subunits of the Arp2/3 complex have been associated with diseases. It's possible that variations in the ARPM1 gene may have functional implications, but further research is needed.

Are there any known cellular processes that require ARPM1 protein?

ARPM1 protein is crucial for various cellular processes where actin dynamics play a significant role, including cell migration, cell shape changes, cell adhesion, endocytosis, vesicle trafficking, and membrane remodeling.

Can ARPM1 protein interact with other proteins or complexes?

ARPM1 interacts with other subunits of the Arp2/3 complex, as well as actin-binding proteins, signaling molecules, and adaptor proteins. These interactions are essential for the proper functioning of the Arp2/3 complex and actin dynamics.