Recombinant Mouse As3mt Protein, Myc/DDK-tagged

• Cat.No.: As3mt-1732M
• Product Overview: Purified recombinant protein of mouse full-length arsenic (+3 oxidation state) methyltransferase (As3mt), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO3H2, which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me2As(O)-OH.
• Molecular Mass: 41.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: As3mt arsenite methyltransferase [ Mus musculus (house mouse) ]
• Official Symbol: As3mt
• Synonyms: AS3MT; arsenic (+3 oxidation state) methyltransferase; arsenite methyltransferase; methyltransferase Cyt19; methylarsonite methyltransferase; S-adenosylmethionine:arsenic (III) methyltransferase; S-adenosyl-L-methionine:arsenic(III) methyltransferase; Cyt19; 2310045H08Rik
• Gene ID: 57344
• mRNA Refseq: NM_020577
• Protein Refseq: NP_065602
• UniProt ID: Q91WU5