Recombinant Mouse Bcl2l1 protein, His-tagged

• Cat.No.: Bcl2l1-74M
• Product Overview: Recombinant mouse BCL2L1, fused to His-tag at N-terminus was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Mouse
• Source: Insect Cells
• Tag: His
• Description: BCL2L1 also known as Bcl-2-like protein 1 isoform a. This protein is a member of BCL-2 protein family. BCL2L1 is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. Also, BCL2L1 controls a switch between cell death modes during mitotic arrest.
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol
• Molecular Mass: 25.8kDa (232aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSQSNRE LVVDFLSYKL SQKGYSWSQF SDVEENRTEA PEETEAERET PSAINGNPSW HLADSPAVNGATGHSSSLDA REVIPMAAVK QALREAGDEF ELRYRRAFSD LTSQLHITPG TAYQSFEQVV NELFRDGVNW GRIVAFFSFG GALCVESVDKEMQVLVSRIA SWMATYLNDH LEPWIQENGG WDTFVDLYGN NAAAESRKGQ ER
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Bcl2l1 BCL2-like 1 [ Mus musculus ]
• Official Symbol: Bcl2l1
• Synonyms: BCL2L1; BCL2-like 1; bcl-2-like protein 1; bcl2-L-1; apoptosis regulator Bcl-X; B-cell leukemia/lymphoma x; anti-apoptosis regulatory protein; BclX; Bcl2l; bcl-x; Bcl-XL; Bcl-Xs; Bcl(X)L; MGC99998; MGC113803
• Gene ID: 12048
• mRNA Refseq: NM_009743
• Protein Refseq: NP_033873
• Pathway: Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis signaling pathway, organism-specific biosystem; Chronic myeloid leukemia, organism-specific biosystem
• Function: BH domain binding; BH3 domain binding; MDM2 binding; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; identical protein binding; protein binding; protein heterodimerization activity; protein heterodimerization activity; protei