Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

Recombinant Mouse Bcl6 Protein, MYC/DDK-tagged

Cat.No. : Bcl6-701M
Product Overview : Purified recombinant protein of full-length mouse B cell leukemia/lymphoma 6 (Bcl6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
  • Related Products
Description : Broad expression in thymus adult (RPKM 22.9), subcutaneous fat pad adult (RPKM 15.7) and 20 other tissues.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 79 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Bcl6 B cell leukemia/lymphoma 6 [ Mus musculus (house mouse) ]
Official Symbol : Bcl6
Synonyms : Bcl6; B cell leukemia/lymphoma 6; Bcl5; B-cell lymphoma 6 protein homolog; B-cell leukemia/lymphoma 5
Gene ID : 12053
mRNA Refseq : NM_009744
Protein Refseq : NP_033874
UniProt ID : P41183

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
What are the current challenges in targeting BCL6 protein for therapeutic purposes? 02/21/2023

Challenges include the need to develop specific and effective inhibitors of BCL6 function while minimizing off-target effects and ensuring tolerability in clinical settings.

Are there any known genetic mutations or alterations in the BCL6 gene associated with disease susceptibility? 10/07/2022

Yes, genetic mutations and translocations involving the BCL6 gene have been linked to the development of certain lymphomas and other hematological malignancies.

What role does BCL6 protein play in the germinal center reaction? 06/13/2022

BCL6 protein is crucial for the formation and maintenance of germinal centers, where it regulates the processes of somatic hypermutation and class-switch recombination in B cells.

How might targeting BCL6 protein offer new therapeutic options for autoimmune diseases? 06/30/2021

Targeting BCL6 protein could potentially offer new therapeutic options by modulating immune responses and suppressing the aberrant production of autoantibodies in autoimmune diseases.

Can the assessment of BCL6 protein expression aid in the prognosis of lymphoma patients? 05/22/2017

Yes, the assessment of BCL6 protein expression can provide valuable prognostic information, helping to predict patient outcomes and guide treatment strategies for lymphoma patients.

Customer Reviews (3)

Write a review
Reviews
04/21/2022

    Its stability and structural integrity make it an ideal candidate for studying protein structures at high resolution.

    09/22/2021

      I am delighted to highly recommend the BCL6 Protein for researchers seeking excellent performance in Western blotting (WB) experiments and protein electron microscopy structure analysis

      12/11/2016

        Its exceptional purity and integrity ensure clear and reliable bands, enabling accurate detection and quantification of target proteins.

        Ask a Question for All Bcl6 Products

        Required fields are marked with *

        My Review for All Bcl6 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends