Recombinant Mouse Bcl6 Protein, MYC/DDK-tagged
Cat.No. : | Bcl6-701M |
Product Overview : | Purified recombinant protein of full-length mouse B cell leukemia/lymphoma 6 (Bcl6), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Broad expression in thymus adult (RPKM 22.9), subcutaneous fat pad adult (RPKM 15.7) and 20 other tissues. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 79 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Bcl6 B cell leukemia/lymphoma 6 [ Mus musculus (house mouse) ] |
Official Symbol : | Bcl6 |
Synonyms : | Bcl6; B cell leukemia/lymphoma 6; Bcl5; B-cell lymphoma 6 protein homolog; B-cell leukemia/lymphoma 5 |
Gene ID : | 12053 |
mRNA Refseq : | NM_009744 |
Protein Refseq : | NP_033874 |
UniProt ID : | P41183 |
Products Types
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BCL6-996M | Recombinant Mouse BCL6 Protein, His (Fc)-Avi-tagged | +Inquiry |
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◆ Lysates | ||
BCL6-8479HCL | Recombinant Human BCL6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionChallenges include the need to develop specific and effective inhibitors of BCL6 function while minimizing off-target effects and ensuring tolerability in clinical settings.
Yes, genetic mutations and translocations involving the BCL6 gene have been linked to the development of certain lymphomas and other hematological malignancies.
BCL6 protein is crucial for the formation and maintenance of germinal centers, where it regulates the processes of somatic hypermutation and class-switch recombination in B cells.
Targeting BCL6 protein could potentially offer new therapeutic options by modulating immune responses and suppressing the aberrant production of autoantibodies in autoimmune diseases.
Yes, the assessment of BCL6 protein expression can provide valuable prognostic information, helping to predict patient outcomes and guide treatment strategies for lymphoma patients.
Customer Reviews (3)
Write a reviewIts stability and structural integrity make it an ideal candidate for studying protein structures at high resolution.
I am delighted to highly recommend the BCL6 Protein for researchers seeking excellent performance in Western blotting (WB) experiments and protein electron microscopy structure analysis
Its exceptional purity and integrity ensure clear and reliable bands, enabling accurate detection and quantification of target proteins.
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