Recombinant Mouse BLM Protein (684-859 aa), His-Myc-tagged

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Recombinant Mouse BLM Protein (684-859 aa), His-Myc-tagged

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Cat.No. : BLM-2206M
Product Overview : Recombinant Mouse BLM Protein (684-859 aa) is produced by E. coli expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Research Area: Neuroscience. Protein Description: Partial.
Description : Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).
Source : E. coli
Species : Mouse
Tag : His-Myc
Form : Tris-based buffer,50% glycerol
Molecular Mass : 24.7 kDa
Protein length : 684-859 aa
AA Sequence : INAALLGEDC FILMPTGGGK SLCYQLPACV SPGVTIVISP LRSLIVDQVQ KLTSFDIPAT YLTGDKTDSE AANIYLQLSK KDPIIKLLYV TPEKVCASNR LISTLENLYE RKLLARFVID EAHCVSQWGH DFRQDYKRMN MLRQKFPSVP VMALTATANP RVQKDILTQL KILRPQ
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : Blm Bloom syndrome, RecQ helicase-like [ Mus musculus ]
Official Symbol : BLM
Synonyms : BLM; Bloom syndrome protein homolog; mBLM; recQ helicase homolog; Bloom syndrome homolog;
Gene ID : 12144
mRNA Refseq : NM_001042527
Protein Refseq : NP_001035992
UniProt ID : O88700
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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