"Bmp4" Related Products

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Recombinant Mouse Bmp4 protein, His/S-tagged

Cat.No.: Bmp4-214M
Product Overview: Recombinant Mouse Bmp4 fused with His/S tag was expressed in E. coli.
Description: Human BMP-4 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor ß (TGF-ß) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation. However, they havesince been shown to be involved in embryogenesis and morphogenesis of various tissues and organs. BMPs have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. BMP-4 is synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
Source: E. coli
Species: Mouse
Tag : His/S
Form: Lyophilized from sterile PBS, pH 7.4
Purity: > 95 % as determined by SDS-PAGE
Storage: Store at -70 centigrade. Avoid repeated freeze/thaw cycles.
Gene Name: Bmp4 bone morphogenetic protein 4 [ Mus musculus ]
Official Symbol: Bmp4
Synonyms: BMP4; bone morphogenetic protein 4; BMP-2B; bone morphogenetic protein 2B; Bmp-4; Bmp2b; Bmp2b1; Bmp2b-1;
Gene ID: 12159
mRNA Refseq: NM_007554
Protein Refseq: NP_031580
UniProt ID: P21275
Chromosome Location: 14 C1; 14 23.95 cM
Pathway: Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; ESC Pluripotency Pathways, organism-specific biosystem; Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem; Pathways in cancer, organism-specific biosystem;
Function: BMP receptor binding; chemoattractant activity; cytokine activity; growth factor activity; heparin binding; protein binding; protein homodimerization activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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