Recombinant Mouse Bmpr2 Protein, MYC/DDK-tagged
Cat.No. : | Bmpr2-715M |
Product Overview : | Purified recombinant protein of full-length mouse bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. |
Source : | HEK293T |
Species : | Mouse |
Tag : | MYC/DDK |
Molecular Mass : | 115.5 kDa |
Purity : | >80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Bmpr2 bone morphogenetic protein receptor, type II (serine/threonine kinase) [ Mus musculus (house mouse) ] |
Official Symbol : | Bmpr2 |
Synonyms : | Bmpr2; bone morphogenetic protein receptor, type II (serine/threonine kinase); BMP-2; BRK-3; BMPR-2; BMPRII; BMPR-II; Gm20272; AL117858; AW546137; BB189135; 2610024H22Rik; bone morphogenetic protein receptor type-2; BMP type II receptor; BMP type-2 receptor; bone morphogenic protein receptor, type II (serine/threonine kinase); EC 2.7.11.30 |
Gene ID : | 12168 |
mRNA Refseq : | NM_007561 |
Protein Refseq : | NP_031587 |
UniProt ID : | O35607 |
Products Types
◆ Recombinant Protein | ||
BMPR2-1060M | Recombinant Mouse BMPR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMPR2-2707H | Recombinant Human BMPR2 Protein, MYC/DDK-tagged | +Inquiry |
BMPR2-377R | Recombinant Rhesus Macaque BMPR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMPR2-451H | Recombinant Human BMPR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
BMPR2-1375H | Recombinant Human BMPR2 Protein (Ser27-Ile151), C-His tagged | +Inquiry |
◆ Lysates | ||
BMPR2-2717HCL | Recombinant Human BMPR2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionBMPR2 plays a significant role in PAH, influencing vascular cell proliferation and vascular remodeling.
Mutations in BMPR2 contribute to hereditary hemorrhagic telangiectasia, impacting vascular development.
Changes in BMPR2 signaling impact embryonic development, potentially resulting in congenital anomalies.
Dysregulation of BMPR2 affects renal function, potentially leading to kidney disease and dysfunction.
BMPR2 is key in bone morphogenetic protein signaling, crucial for bone growth and remodeling.
BMPR2 is involved in cardiovascular development, particularly affecting heart valve formation and function.
BMPR2 regulates cell proliferation and apoptosis, playing a role in tissue homeostasis.
Customer Reviews (3)
Write a reviewHigh-quality protein crystallography services, exceptional outcomes.
Critical expertise in protein engineering, unmatched service quality.
Swift and reliable protein sequencing, invaluable for our research.
Ask a Question for All Bmpr2 Products
Required fields are marked with *
My Review for All Bmpr2 Products
Required fields are marked with *
Inquiry Basket