Recombinant Mouse Calca Protein, MYC/DDK-tagged

• Cat.No.: Calca-745M
• Product Overview: Purified recombinant protein of full-length mouse calcitonin/calcitonin-related polypeptide, alpha (Calca), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide (CGRP) and katacalcin. Alternative splicing of the mRNA results in multiple variants that encode either calcitonin or CGRP preproproteins. Post-translational processing of the calcitonin and CGRP propeptides results in either calcitonin and katacalcin, or CGRP, respectively. Calcitonin and katacalcin modulate calcium levels in the blood stream. CGRP can function as a vasodilator and play a role in the transmission of pain. The human homolog of CGRP was found to have antimicrobial activity.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 14.1 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Calca calcitonin/calcitonin-related polypeptide, alpha [ Mus musculus (house mouse) ]
• Official Symbol: Calca
• Synonyms: Calca; calcitonin/calcitonin-related polypeptide, alpha; CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1; calcitonin gene-related peptide 1; alpha-type CGRP; calcitonin gene-related peptide I
• Gene ID: 12310
• mRNA Refseq: NM_001033954
• Protein Refseq: NP_001029126
• UniProt ID: Q99JA0