Recombinant Mouse Calcoco1 Protein, Myc/DDK-tagged
Cat.No. : | Calcoco1-1935M |
Product Overview : | Purified recombinant protein of mouse full-length calcium binding and coiled coil domain 1 (Calcoco1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions. In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 77.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Calcoco1 calcium binding and coiled coil domain 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Calcoco1 |
Synonyms : | CALCOCO1; calcium binding and coiled coil domain 1; calcium-binding and coiled-coil domain-containing protein 1; GRIP1-interacting protein; coiled-coil coactivator protein; granule cell antiserum positive 11; coiled-coil transcriptional coactivator; Cocoa; Gcap11; mKIAA1536; 1810009B06Rik; KIAA1536 |
Gene ID : | 67488 |
mRNA Refseq : | NM_026192 |
Protein Refseq : | NP_080468 |
UniProt ID : | Q8CGU1 |
Products Types
◆ Recombinant Protein | ||
CALCOCO1-1187M | Recombinant Mouse CALCOCO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CALCOCO1-753R | Recombinant Rat CALCOCO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CALCOCO1-0292H | Recombinant Human CALCOCO1 Protein, GST-Tagged | +Inquiry |
CALCOCO1-2645M | Recombinant Mouse CALCOCO1 Protein | +Inquiry |
CALCOCO1-1089R | Recombinant Rat CALCOCO1 Protein | +Inquiry |
◆ Lysates | ||
CALCOCO1-7894HCL | Recombinant Human CALCOCO1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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