Recombinant Mouse CALR Protein (18-416 aa), GST-tagged

• Cat.No.: CALR-377M
• Product Overview: Recombinant Mouse CALR Protein (18-416 aa) is produced by E. coli expression system. This protein is fused with a GST tag at the N-terminal. Protein Description: Full Length of Mature Protein.

Specification

• Description: Calcium-binding chaperone that promotes folding, oligomeric assbly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis .
• Source: E. coli
• Species: Mouse
• Tag: GST
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 73.3 kDa
• Protein length: 18-416 aa
• AA Sequence: DPAIYFKEQFLDGDAWTNRWVESKH KSDFGKFVLSSGKFYGDLEKDKGLQ TSQDARFYALSAKFEPFSNKGQTLV VQFTVKHEQNIDCGGGYVKLFPSGL DQKDMHGDSEYNIMFGPDICGPGTK KVHVIFNYKGKNVLINKDIRCKDDE FTHLYTLIVRPDNTYEVKIDNSQVE SGSLEDDWDFLPPKKIKDPDAAKPE DWDERAKIDDPTDSKPEDWDKPEHI PDPDAKKPEDWDEEMDGEWEPPVIQ NPEYKGEWKPRQIDNPDYKGTWIHP EIDNPEYSPDANIYAYDSFAVLGLD LWQVKSGTIFDNFLITNDEAYAEEF GNETWGVTKAAEKQMKDKQDEEQRL KEEEEDKKRKEEEEAEDKEDDDDRD EDEDEEDEKEEDEEESPGQAKDEL
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: Calr calreticulin [ Mus musculus ]
• Official Symbol: CALR
• Synonyms: CALR; calreticulin; CRP55; ERp60; HACBP; CRT; Calregulin
• Gene ID: 12317
• mRNA Refseq: NM_007591
• Protein Refseq: NP_031617
• UniProt ID: P14211