Recombinant Mouse Caspase 8
Cat.No. : | Casp8-1645M |
Product Overview : | Recombinant active mouse caspase-8 was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Casp8-1645M |
Description : | Casp8 (also know as FLICE, MASH, Mch5) is a member of the caspase-family of cysteine proteases. Similar to other caspases, casp8 also exists in cells as an inactive proenzyme. During apoptosis procaspase-8 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of casp8 consists of large and small subunits which associate to form the active enzyme. |
Biological Activity : | 5000 units/mg |
Source : | E. coli |
Species : | Mouse |
Form : | Lyophilized powder. |
Appearance : | Lyophilized powder |
Reconstitution : | Reconstitute to 1 unit per µl in PBS containing 15% glycerol. |
Purity : | ≥ 95 % by SDS-PAGE |
Storage : | The lyophilized caspase-8 is stable for 1 year at -70°C. Following reconstitution in PBS, the enzyme should be aliquoted and immediately stored at -70°C. Avoid multiple freeze/thaw cycles as activity might decrease. |
Pathways : | Activation of Pro-Caspase 8; Activation; Alzheimer"s disease; Androgen Receptor Signaling Pathway; Apoptosis; Apoptosis Modulation by HSP70; Apoptotic cleavage of cellular proteins; Apoptotic execution phase; Death Receptor Signalling; Extrinsic Pathway for Apoptosis; Herpes simplex infection; Huntington"s disease; Intrinsic Pathway for Apoptosis; Legionellosis; MAPK signaling pathway |
Gene Name : | Casp8 caspase 8 [ Mus musculus ] |
Official Symbol : | Casp8 |
Synonyms : | Casp8; caspase 8; MACH; Mch5; FLICE; CASP-8; caspase-8; Fas-linked ICE-like protease; Caspase-8; EC 3.4.22.61 |
Gene ID : | 12370 |
mRNA Refseq : | NM_001080126 |
Protein Refseq : | NP_001073595 |
UniProt ID : | O89110 |
Chromosome Location : | 1 B; 1 30.1 cM |
Function : | cysteine-type endopeptidase activity; cysteine-type peptidase activity; hydrolase activity; identical protein binding; peptidase activity; protein binding; tumor necrosis factor receptor binding |
Products Types
◆ Recombinant Protein | ||
CASP8-804R | Recombinant Rat CASP8 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP8-1247M | Recombinant Mouse CASP8 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP8-4937H | Recombinant Human CASP8 Protein(217–374aa), His-tagged | +Inquiry |
CASP8-26606TH | Active Recombinant Human CASP8 Protein | +Inquiry |
CASP8-2756M | Recombinant Mouse CASP8 Protein | +Inquiry |
◆ Lysates | ||
CASP8-7830HCL | Recombinant Human CASP8 293 Cell Lysate | +Inquiry |
CASP8-7829HCL | Recombinant Human CASP8 293 Cell Lysate | +Inquiry |
CASP8-7831HCL | Recombinant Human CASP8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket