- Mouse(7)
Recombinant Mouse Ccl12 Protein (82 aa)
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Cat.No. : | Ccl12-224C Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Mouse MCP-5/CCL1 produced in CHO cells is a polypeptide chain containing 82 amino acids. A fully biologically active molecule, rmMCP-5/CCL12 has a molecular mass of 11 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
Description : | Monocyte Chemotactic Protein-5(MCP-5), also known as Chemokine (C-C motif) ligand 12(CCL12), is a small cytokine belonging to the CC chemokine family that has been characterized in mice. Due to its similarity with human chemokine MCP-1, sometimes it is called MCP-1-related chemokine. MCP-5 specifically attracts eosinophils, monocytes and lymphocytes.It can signal through the CCR2 receptor. |
Source : | CHO |
Species : | Mouse |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | The EC50 value of mouse MCP-5/CCL12 on Ca^2+ mobilization assay in CHO-K1/Gα15/mCCR2 cells (human Gα15 and mouse CCR2 stably expressed in CHO-K1 cells) is less than 0.5 μg/mL. |
Molecular Mass : | 9.3-11 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 82 |
AA Sequence : | GPDAVSTPVT CCYNVVKQKI HVRKLKSYRR ITSSQCPREA VIFRTILDKE ICADPKEKWV KNSINHLDKT SQTFILEPSC LG |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 98% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant Mouse MCP-5/CCL12 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Mouse MCP-5/CCL12 should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name : | Ccl12 chemokine (C-C motif) ligand 12 [ Mus musculus ] |
Official Symbol : | Ccl12 |
Synonyms : | CCL12; chemokine (C-C motif) ligand 12; C-C motif chemokine 12; MCP-1-related chemokine; small inducible cytokine A12; small-inducible cytokine A12; monocyte chemotactic protein 5; monocyte chemoattractant protein 5; MCP-5; Scya12; |
Gene ID : | 20293 |
mRNA Refseq : | NM_011331 |
Protein Refseq : | NP_035461 |
UniProt ID : | Q545B5 |
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