Active Recombinant Mouse Ccl19 Protein

• Cat.No.: Ccl19-2029M
• Product Overview: Purified recombinant protein of Mouse chemokine (C-C motif) ligand 19 (Ccl19 / MIP-3beta) without tag was expressed in HEK293.

Specification

• Description: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
• Source: HEK293
• Species: Mouse
• Bio-activity: Bioactivity was measured by its property to chemoattract Baf3-hCCR7 transfectants in a dose dependent manner.
• Molecular Mass: 9.3 kDa
• Protein length: Gly26-Val107-Leu-Glu
• Endotoxin: Less than 0.01 ng/μg protein as determined by the LAL method
• Purity: > 95%, as determined by Coomassie stained SDS-PAGE.
• Stability: Unopened vial can be stored between 2 and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: Protein formulated and vialed at >50 μg/mL in specified buffer
• Storage Buffer: 1 x PBS

Gene Information

• Gene Name: Ccl19 chemokine (C-C motif) ligand 19 [ Mus musculus (house mouse) ]
• Official Symbol: Ccl19
• Synonyms: Ccl19; chemokine (C-C motif) ligand 19; ELC; Scya; CKb11; MIP3B; Gm2023; Scya19; exodus; exodus-3; 100039053; C-C motif chemokine 19; EBI-1 ligand chemokine; EBI1 ligand chemokine; EBV-induced molecule 1 ligand chemokine; chemokine CCL19; epstein-Barr virus-induced molecule 1 ligand chemokine; small-inducible cytokine A19
• Gene ID: 24047
• mRNA Refseq: NM_011888
• Protein Refseq: NP_036018
• UniProt ID: O70460