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Recombinant Mouse Ccl2 Protein
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Cat.No. : | Ccl2-130M Optional Service: Optional requirements on this protein |
Product Overview : | Purified recombinant protein of Mouse chemokine (C-C motif) ligand 2 (Ccl2) without tag was expressed in E.coli. |
Description : | This gene is one of several cytokine genes clustered on chromosome 11. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and memory T cells but not for neutrophils. The human ortholog has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, such as psoriasis, rheumatoid arthritis, and atherosclerosis. |
Source : | E. coli |
Species : | Mouse |
Bio-activity : | Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml. |
Molecular Mass : | 13.8 kDa |
AA Sequence : | QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN |
Endotoxin : | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Purity : | >95%, as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. |
Storage Buffer : | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2 |
Reconstitution : | Resuspend the protein in the desired concentration in proper buffer. |
Figure : |
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Gene Name : | Ccl2 chemokine (C-C motif) ligand 2 [ Mus musculus (house mouse) ] |
Official Symbol : | Ccl2 |
Synonyms : | Ccl2; chemokine (C-C motif) ligand 2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594; C-C motif chemokine 2; monocyte chemoattractant protein 1; monocyte chemotactic protein 1; platelet-derived growth factor-inducible protein JE; small-inducible cytokine A2 |
Gene ID : | 20296 |
mRNA Refseq : | NM_011333 |
Protein Refseq : | NP_035463 |
UniProt ID : | P10148 |
◆ Recombinant Protein
CCL2-869R | Recombinant Rat CCL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCL2-2146C | Recombinant Cattle CCL2 Protein, His-tagged | +Inquiry |
CCL2-14H | Recombinant Human CCL2 Protein | +Inquiry |
CCL2-1102C | Recombinant Cattle CCL2 Protein, His-tagged | +Inquiry |
Ccl2-2031M | Recombinant Mouse Ccl2 Protein, Myc/DDK-tagged | +Inquiry |
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◆ Lysates
CCL2-001MCL | Recombinant Mouse CCL2 cell lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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