Recombinant Mouse Cd34 protein, His & GST-tagged

• Cat.No.: Cd34-2019M
• Product Overview: Recombinant Mouse Cd34 aa. (Thr36~Thr287 (Accession # Q64314)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Mouse
• Tag: His & GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 59.1kDa
• Protein length: Thr36~Thr287 (Accession # Q64314)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Cd34 CD34 antigen [ Mus musculus (house mouse) ]
• Official Symbol: Cd34
• Synonyms: ABCC4; ATP binding cassette subfamily C member 4; MRP4; MOATB; MOAT-B; multidrug resistance-associated protein 4; MRP/cMOAT-related ABC transporter; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); multi-specific organic anion transporter B
• Gene ID: 12490
• mRNA Refseq: NM_001111059.1
• Protein Refseq: NP_001104529.1
• UniProt ID: Q64314

Reviews

07/02/2022

CD34 protein may have a specific binding affinity or interaction with its target molecules or receptors, making it a valuable tool for targeted therapies or diagnostic applications.

04/06/2019

In some cases, manufacturers may be open to collaborating with researchers to further investigate the applications and potential of CD34 protein.

03/03/2018

If researchers require modifications or specific variants of CD34 protein for their experiments, the manufacturer could potentially offer custom protein engineering services to meet their needs.

01/30/2016

This collaboration can involve sharing resources, expertise, and data to advance scientific understanding and therapeutic development.

Q&As

How is CD34 used in the assessment of bone marrow health?

CD34 is employed as a marker to evaluate the status of bone marrow, aiding in the diagnosis and monitoring of disorders affecting the bone marrow.

How does CD34 impact the prognosis of hematologic diseases?

CD34 expression levels are sometimes correlated with the prognosis of certain hematologic diseases, helping clinicians predict disease outcomes and plan appropriate interventions.

How does CD34 contribute to the understanding of hematologic malignancies?

CD34 expression patterns are studied to gain insights into the pathogenesis and progression of hematologic malignancies, aiding in the development of targeted therapies.

Can CD34 be used to monitor the effectiveness of cancer treatments?

Yes, changes in CD34 expression can be indicative of the response to cancer treatments, providing valuable information for patient management.

Are there any specific therapeutic applications of CD34?

CD34 is a target for therapeutic interventions, and research is ongoing to explore its potential for developing treatments for various diseases.

Is CD34 exclusively used in hematological research, or does it have applications in other medical fields?

While CD34 is prominently used in hematological research, its role in angiogenesis extends its applications to cardiovascular research and regenerative medicine.