Recombinant Mouse Cd55 Protein, His-tagged
Cat.No. : | Cd55-695M |
Product Overview : | Recombinant Mouse Cd55(Pro47~Glu286) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an inhibitor of both the classical and the alternative pathways of complement activation. The encoded preproprotein undergoes post-translational processing to generate a mature polypeptide anchored to the plasma membrane via a glycosylphosphatidylinositol moiety. Erythrocytes from mice deficient in the encoded protein exhibit impaired regulation of complement activation resulting in enhanced complement deposition. Mice lacking the encoded protein exhibit enhanced susceptibility to experimentally induced myasthenia gravis. This gene is located adjacent to a closely related gene on chromosome 1. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 28.1kDa |
Identity : | Reconstitute in PBS or others |
Protein length : | Pro47~Glu286 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | Cd55 CD55 antigen [ Mus musculus ] |
Official Symbol : | Cd55 |
Synonyms : | CD55; CD55 antigen; complement decay-accelerating factor, GPI-anchored; Cromer blood group; GPI anchor addition signal; decay accelerating factor 1; complement-glycosylphosphatidylinositol; Daf; Daf1; Daf-GPI; GPI-DAF; |
Gene ID : | 13136 |
mRNA Refseq : | NM_010016 |
Protein Refseq : | NP_034146 |
UniProt ID : | Q61475 |
Products Types
◆ Recombinant Protein | ||
CD55-2325H | Recombinant Human CD55 Protein, GST-tagged | +Inquiry |
CD55-01H | Recombinant Human CD55 Protein (35-353aa), C-His-tagged | +Inquiry |
CD55-2590H | Recombinant Human CD55 protein(231-350 aa), C-His-tagged | +Inquiry |
Cd55-6893M | Recombinant Mouse Cd55 protein(Met1-Thr361), His-tagged | +Inquiry |
CD55-64H | Active Recombinant Human CD55 protein(Met1-Ser353), hFc-tagged | +Inquiry |
◆ Lysates | ||
CD55-2531HCL | Recombinant Human CD55 cell lysate | +Inquiry |
CD55-1433RCL | Recombinant Rat CD55 cell lysate | +Inquiry |
CD55-1669MCL | Recombinant Mouse CD55 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionGenetic variations in CD55 may influence susceptibility to complement-mediated disorders by affecting the protein's ability to regulate complement activation. This can lead to conditions like paroxysmal nocturnal hemoglobinuria (PNH).
CD55 has immunomodulatory functions beyond complement regulation, influencing T cell responses and contributing to the maintenance of immune tolerance.
CD55 protects cells from complement-mediated lysis by preventing the formation of membrane attack complexes. This contributes to immune evasion by pathogens and self-cells alike.
CD55 consists of extracellular domains responsible for interactions with complement proteins, particularly C3b and C4b. These interactions prevent the formation of membrane attack complexes on host cells.
CD55 dysregulation is associated with autoimmune disorders, where it may contribute to immune system overactivity. Additionally, some pathogens exploit CD55 to evade host immune responses.
Customer Reviews (3)
Write a reviewEfficient shipping and exceptional product quality. This company knows how to serve its customers.
Consistency is key in research, and this product delivers that every time.
We've tried various proteins, but this one stands out for its purity and performance.
Ask a Question for All Cd55 Products
Required fields are marked with *
My Review for All Cd55 Products
Required fields are marked with *
Inquiry Basket