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Recombinant Mouse Cdk14 Protein, Myc/DDK-tagged

Cat.No. : Cdk14-4814M
Product Overview : Purified recombinant protein of mouse full-length PFTAIRE protein kinase 1 (cDNA clone MGC:95907 IMAGE:6834018), complete cds, with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 47.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cdk14 cyclin-dependent kinase 14 [ Mus musculus (house mouse) ]
Official Symbol : Cdk14
Synonyms : Cdk14; cyclin-dependent kinase 14; Pftk; Pftk1; mKIAA0834; cyclin-dependent kinase 14; cell division protein kinase 14; serine/threonine-protein kinase PFTAIRE-1; EC 2.7.11.22
Gene ID : 18647
mRNA Refseq : NM_011074
Protein Refseq : NP_035204
UniProt ID : O35495

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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