Recombinant Mouse Cdkn2c Protein, MYC/DDK-tagged Cdkn2c-871M

Recombinant Mouse Cdkn2c Protein, MYC/DDK-tagged

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Recombinant Mouse Cdkn2c Protein, MYC/DDK-tagged

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Cat.No. : Cdkn2c-871M
Product Overview : Purified recombinant protein of full-length mouse cyclin dependent kinase inhibitor 2C (Cdkn2c), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase (cdk) inhibitors, and contains five ankyrin repeats. This protein interacts with both Cdk4 and Cdk6 to inhibit their kinase activities, and prevent their interactions with D-type cyclins, thereby negatively regulating cell division. This gene is differentially expressed in a variety of tissues, and is cell cycle regulated. Deletion of this gene can lead to tumor growth. Maximal expression is observed at the G2/M phase. Alternative splicing and promoter usage results in multiple transript variants.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 18.1 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cdkn2c cyclin dependent kinase inhibitor 2C [ Mus musculus (house mouse) ]
Official Symbol : Cdkn2c
Synonyms : Cdkn2c; cyclin dependent kinase inhibitor 2C; p18; INK4c; C77269; p18-INK6; p18INK4c; p18-INK4c; cyclin-dependent kinase 4 inhibitor C; cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Gene ID : 12580
mRNA Refseq : NM_007671
Protein Refseq : NP_031697
UniProt ID : Q60772

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