Recombinant Mouse Cdkn2c Protein, MYC/DDK-tagged


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Recombinant Mouse Cdkn2c Protein, MYC/DDK-tagged

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Cat.No. : Cdkn2c-871M
Product Overview : Purified recombinant protein of full-length mouse cyclin dependent kinase inhibitor 2C (Cdkn2c), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.
Description : The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase (cdk) inhibitors, and contains five ankyrin repeats. This protein interacts with both Cdk4 and Cdk6 to inhibit their kinase activities, and prevent their interactions with D-type cyclins, thereby negatively regulating cell division. This gene is differentially expressed in a variety of tissues, and is cell cycle regulated. Deletion of this gene can lead to tumor growth. Maximal expression is observed at the G2/M phase. Alternative splicing and promoter usage results in multiple transript variants.
Source : HEK293T
Species : Mouse
Molecular Mass : 18.1 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 µg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cdkn2c cyclin dependent kinase inhibitor 2C [ Mus musculus (house mouse) ]
Official Symbol : Cdkn2c
Synonyms : Cdkn2c; cyclin dependent kinase inhibitor 2C; p18; INK4c; C77269; p18-INK6; p18INK4c; p18-INK4c; cyclin-dependent kinase 4 inhibitor C; cyclin-dependent kinase 6 inhibitor; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Gene ID : 12580
mRNA Refseq : NM_007671
Protein Refseq : NP_031697
UniProt ID : Q60772
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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