Recombinant Mouse Celf6 Protein, Myc/DDK-tagged

• Cat.No.: Celf6-2102M
• Product Overview: Purified recombinant protein of mouse full-length CUGBP, Elav-like family member 6 (Celf6), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 48.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Celf6 CUGBP, Elav-like family member 6 [ Mus musculus (house mouse) ]
• Official Symbol: Celf6
• Synonyms: Celf6; CUGBP, Elav-like family member 6; Bru; Brunol6; 6330569O16Rik; CUGBP Elav-like family member 6; CUG-BP- and ETR-3-like factor 6; RNA-binding protein BRUNOL-6; bruno-like 6, RNA binding protein; bruno-like protein 6; EC 3.2.1.52
• Gene ID: 76183
• mRNA Refseq: NM_175235
• Protein Refseq: NP_780444
• UniProt ID: Q7TN33