Recombinant Mouse Cipc Protein, Myc/DDK-tagged

• Cat.No.: Cipc-2167M
• Product Overview: Purified recombinant protein of mouse full-length CLOCK interacting protein, circadian (Cipc), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK. However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock.
• Molecular Mass: 42.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cipc CLOCK interacting protein, circadian [ Mus musculus (house mouse) ]
• Official Symbol: Cipc
• Synonyms: Cipc; CLOCK interacting protein, circadian; AI842544; AI853744; 2310044G17Rik; CLOCK-interacting pacemaker; CLOCK-interacting circadian protein
• Gene ID: 217732
• mRNA Refseq: NM_173735
• Protein Refseq: NP_776096
• UniProt ID: Q8R0W1