Recombinant Mouse Cln5 Protein, Myc/DDK-tagged

• Cat.No.: Cln5-2193M
• Product Overview: Purified recombinant protein of mouse full-length ceroid-lipofuscinosis, neuronal 5 (Cln5), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 39.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Cln5 ceroid-lipofuscinosis, neuronal 5 [ Mus musculus (house mouse) ]
• Official Symbol: Cln5
• Synonyms: Cln5; ceroid-lipofuscinosis, neuronal 5; A730075N08Rik; ceroid-lipofuscinosis neuronal protein 5 homolog
• Gene ID: 211286
• mRNA Refseq: NM_001033242
• Protein Refseq: NP_001028414
• UniProt ID: Q3UMW8