Recombinant Mouse Cox6b2 Protein, Myc/DDK-tagged

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Recombinant Mouse Cox6b2 Protein, Myc/DDK-tagged

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Cat.No. : Cox6b2-2279M
Product Overview : Purified recombinant protein of mouse full-length cytochrome c oxidase subunit 6B2 (Cox6b2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
Description : Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 11 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cox6b2 cytochrome c oxidase subunit 6B2 [ Mus musculus (house mouse) ]
Official Symbol : Cox6b2
Synonyms : COX6B2; cytochrome c oxidase subunit VIb polypeptide 2; cytochrome c oxidase subunit 6B2; COX VIb-2; cytochrome c oxidase subunit VIb, testis-specific isoform; COXVIB2; BC048670; 1700067P11Rik; MGC130249; MGC130250
Gene ID : 333182
mRNA Refseq : NM_183406
Protein Refseq : NP_899665
UniProt ID : Q80ZN9
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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