Recombinant Mouse Crmp1 Protein, Myc/DDK-tagged

• Cat.No.: Crmp1-2316M
• Product Overview: Purified recombinant protein of mouse full-length collapsin response mediator protein 1 (Crmp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a protein that is part of the collapsin response mediator protein family. The family is comprised of five, homologous cytosolic phosphoproteins that are expressed in developing and adult nervous tissue and mediate signaling to transduce responses to extracellular cues. This protein is a Semaphorin 3A signaling molecule that regulates collapse of the growth cone. The growth cone mediates axonal pathfinding in neurons. This protein is reported to represent a new class of microtubule-associated proteins. In humans this protein is reported to inhibit cancer cell invasion. In mouse deficiency of this gene may be associated with impaired spatial memory performance. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 62.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Crmp1 collapsin response mediator protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Crmp1
• Synonyms: CRMP1; collapsin response mediator protein 1; dihydropyrimidinase-related protein 1; CRMP-1; ULIP-3; unc-33-like phosphoprotein 3; DRP-1; Ulip3; Dpysl1
• Gene ID: 12933
• mRNA Refseq: NM_007765
• Protein Refseq: NP_031791
• UniProt ID: P97427