Recombinant Mouse Cryab Protein

Cat.No. : Cryab-002M
Product Overview : Recombinant Mouse Cryab protein without tag was expressed in E. coli.
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Description : This gene encodes a member of the small heat-shock protein (HSP20) family. The encoded protein is a molecular chaperone that protects proteins against thermal denaturation and other stresses. This protein is a component of the eye lens, regulates lens differentiation and functions as a refractive element in the lens. This protein is a negative regulator of inflammation, has anti-apoptotic properties and also plays a role in the formation of muscular tissue. Mice lacking this gene exhibit worse experimental autoimmune encephalomyelitis and inflammation of the central nervous system compared to the wild type. In mouse models, this gene has a critical role in alleviating the pathology of the neurodegenerative Alexander disease. Mutations in the human gene are associated with myofibrillar myopathy 2, fatal infantile hypertonic myofibrillar myopathy, multiple types of cataract and dilated cardiomyopathy. Alternative splicing results in multiple transcript variants.
Source : E. coli
Species : Mouse
Form : Solution
Molecular Mass : 20 kDa
Protein Length : 175
Purity : > 95%
Applications : WB
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : 4°C
Concentration : 1 mg/mL
Storage Buffer : Tris (pH 8). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : Cryab crystallin, alpha B [ Mus musculus (house mouse) ]
Official Symbol : Cryab
Synonyms : Cryab; crystallin, alpha B; P23; Crya2; HspB5; Crya-2; alpha-crystallin B chain; alpha(B)-crystallin; crystallin, alpha 2; heat shock protein CryAB; heat shock protein HspB5
Gene ID : 12955
mRNA Refseq : NM_009964
Protein Refseq : NP_034094
UniProt ID : P23927

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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