"CTGF" Related Products

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Recombinant Mouse CTGF protein, His-tagged

Cat.No. : CTGF-393M
Product Overview : Recombinant Mouse CTGF protein (Gln26-Ala348), fused to His tag at C-terminus, was expressed in human 293 cells (HEK293).
Description : Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized from 0.22 um filtered solution in Tris with Potassium glutamate and Arginine, pH7.0, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 37.3 kDa. The protein migrates as 37-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : 323
Endotoxin : Less than 1.0 EU per ug by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
SDS-PAGE of CTGF-393M :

Mouse CTGF, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA of CTGF-393M :

Immobilized Mouse CTGF, His Tag at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CTGF Antibody, Human IgG1 with a linear range of 0.3-5 ng/mL (QC tested).

Gene Name : CTGF
Official Symbol : CTGF
Synonyms : CTGF; connective tissue growth factor; CCN family member 2; fibroblast inducible secreted protein; fibroblast inducible secreated protein; hypertrophic chondrocyte-specific protein 24; hypertrophic chondrocyte-specific gene product 24; Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24); Ccn2; Hcs24; Fisp12; fisp-12
Gene ID : 14219
mRNA Refseq : NM_010217
Protein Refseq : NP_034347
UniProt ID : P29268

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