"Ctsh" Related Products

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Recombinant Mouse Ctsh protein, His & T7-tagged

Cat.No. : Ctsh-8181M
Product Overview : Recombinant Mouse Ctsh aa. (Ala21~Val333 (Accession # P49935)) fused with N-terminal His & T7 tag was produced in E. coli cells.
Description : This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin H mini, heavy, and light chains. In rat and human, these three chains can associate to form the mature enzyme, which has both aminopeptidase and endopeptidase activities. Homozygous knockout mice for this gene exhibit impaired lung surfactant processing and reduced tumorigenesis in a pancreatic cancer model. Multiple pseudogenes of this gene have been identified in the genome.
Source : E. coli
Species : Mouse
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 38.8kDa.
Protein length : Ala21~Val333 (Accession # P49935)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >90%
Characteristic : The isoelectric point is 8.7.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Gene Name : Ctsh cathepsin H [ Mus musculus (house mouse) ]
Official Symbol : Ctsh
Synonyms : Ctsh; cathepsin H; AL022844; pro-cathepsin H; Cat H; cathepsin B3; cathepsin BA
Gene ID : 13036
mRNA Refseq : NM_001312649.1
Protein Refseq : NP_001299578.1
UniProt ID : P49935

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