Recombinant Mouse Ctsh Protein, Myc/DDK-tagged

• Cat.No.: Ctsh-2370M
• Product Overview: Purified recombinant protein of mouse full-length cathepsin H (Ctsh), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin H mini, heavy, and light chains. In rat and human, these three chains can associate to form the mature enzyme, which has both aminopeptidase and endopeptidase activities. Homozygous knockout mice for this gene exhibit impaired lung surfactant processing and reduced tumorigenesis in a pancreatic cancer model. Multiple pseudogenes of this gene have been identified in the genome.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 37.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ctsh cathepsin H [ Mus musculus (house mouse) ]
• Official Symbol: Ctsh
• Synonyms: CTSH; cathepsin H; pro-cathepsin H; Cat H; cathepsin B3; cathepsin BA; AL022844
• Gene ID: 13036
• mRNA Refseq: NM_007801
• Protein Refseq: NP_031827
• UniProt ID: P49935