Recombinant Mouse Ctss protein, His-tagged
Cat.No. : | Ctss-1985M |
Product Overview : | Recombinant Mouse Ctss aa. (Leu123~Glu339) fused with N-terminal His tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. Alternative splicing results in multiple transcript variants, which encode preproproteins that are proteolytically processed to generate mature protein products. This enzyme is secreted by antigen-presenting cells during inflammation and may induce pain and itch via activation of G-protein coupled receptors. Homozygous knockout mice for this gene exhibit impaired wound healing, reduced tumorigenesis in a pancreatic cancer model, and reduced pathogenesis in a myasthenia gravis model. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | 33kDa as determined by SDS-PAGE reducing conditions. |
Protein length : | Leu123~Glu339 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | > 92% |
Characteristic : | The isoelectric point is 5.6. |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200μg/mL |
Storage Buffer : | 10mM PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300. |
Reconstitution : | Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex |
Gene Name : | Ctss cathepsin S [ Mus musculus (house mouse) ] |
Official Symbol : | Ctss |
Synonyms : | Map2k2; mitogen-activated protein kinase kinase 2; MK2; MEK2; Prkmk2; AA589381; dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; MAP kinase kinase 2; MAP kinase/Erk kinase; MAPK/ERK kinase 2; MAPKK 2; MEK 2; protein kinase, mitogen activated, kinase 2, p45 |
Gene ID : | 13040 |
mRNA Refseq : | NM_001267695.2 |
Protein Refseq : | NP_001254624.2 |
UniProt ID : | F6WR04 |
Products Types
◆ Recombinant Protein | ||
Ctss-1293R | Recombinant Rat Ctss Protein, His-tagged | +Inquiry |
CTSS-2118H | Recombinant Human CTSS Protein, GST-tagged | +Inquiry |
CTSS-1329R | Recombinant Rat CTSS Protein, His (Fc)-Avi-tagged | +Inquiry |
CTSS-1984C | Recombinant Cattle CTSS protein, His & T7-tagged | +Inquiry |
CTSS-7251H | Recombinant Human CTSS, His-tagged | +Inquiry |
◆ Native Protein | ||
CTSS-27405TH | Native Human CTSS | +Inquiry |
◆ Lysates | ||
CTSS-3021HCL | Recombinant Human CTSS cell lysate | +Inquiry |
CTSS-1563MCL | Recombinant Mouse CTSS cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2353 | Cathepsin S Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe function of CTSS proteins can be studied through gene knockout or knockdown techniques, such as using techniques such as CRISPR-Cas9 or RNAi. These techniques can create cellular models of missing or reduced CTSS proteins to observe their effects on cell death, among other things.
Expression level of CTSS protein can be detected by immunohistochemistry, western blotting, and real-time quantitative PCR.
CTSS proteins promote cell death by degrading proteins inside cells. During apoptosis, CTSS proteins degrade key proteins within cells, leading to cell death.
The interaction between CTSS proteins and other proteins is regulated by the formation of complexes or the regulation of signal transduction pathways. These interactions can be influenced by a variety of factors, such as ion concentrations, neurotransmitters, and growth factors.
Some studies have shown that the expression level of CTSS protein may be associated with the onset and progression of certain diseases. For example, in some cancers, the expression level of the CTSS protein may change.
It is mainly expressed in lysosomes, which is one of the major proteases in lysosomes.
Customer Reviews (3)
Write a reviewHigh catalytic efficiency, short time, saving time.
The solubility is very good and can be easily dissolved in various buffers.
Anti-pollution ability is very strong, not easy to be polluted.
Ask a Question for All Ctss Products
Required fields are marked with *
My Review for All Ctss Products
Required fields are marked with *
Inquiry Basket