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Recombinant mouse Cxcl12, GST-tagged

Cat.No. : Cxcl12-11719M
Product Overview : Recombinant Mouse Cxcl12 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Description : The protein encoded by this gene is a member of the intercrine-macrophage inflammatory protein superfamily. It is a secreted protein thought to be involved in the generation and proliferation of early B-cell progenitors. Three transcript variants encoding three different isoforms have been found for this gene.
Source : E.coli
Species : Mouse
Tag : GST
Protein length : 1-89a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : Cxcl12 chemokine (C-X-C motif) ligand 12 [ Mus musculus ]
Official Symbol : Cxcl12
Synonyms : CXCL12; chemokine (C-X-C motif) ligand 12; stromal cell-derived factor 1; C-X-C motif chemokine 12; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; thymic lymphoma cell-stimulating factor; 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; Pbsf; Sdf1; Tlsf; Sdf1a; Sdf1b; Tlsfa; Tlsfb; Tpar1; Scyb12; AI174028;
Gene ID : 20315
mRNA Refseq : NM_001012477
Protein Refseq : NP_001012495
Pathway : Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem;
Function : CXCR chemokine receptor binding; chemokine activity; cytokine activity; growth factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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How are researchers using CXCL12 in neurodegenerative disease research? 08/27/2022

CXCL12 is being investigated for its role in neuroprotection and neuroregeneration in conditions like Alzheimer's and Parkinson's disease.

Are there diagnostic tests that measure CXCL12 levels in patients? 12/19/2021

Yes, ELISA and other assays can be used to measure CXCL12 levels, aiding in the diagnosis and monitoring of certain diseases.

Can CXCL12 be used as a biomarker for specific diseases? 02/03/2021

CXCL12 levels can serve as a biomarker for various diseases, such as HIV, cancer, and inflammatory disorders.

How is CXCL12 being researched for cardiovascular therapies? 06/16/2019

Scientists are exploring the potential of CXCL12-based therapies to promote vascular repair and treat heart diseases.

Can CXCL12-based therapies help in spinal cord injury treatment? 04/02/2019

Researchers are studying CXCL12-based treatments to promote nerve regeneration and functional recovery after spinal cord injuries.

Customer Reviews (3)

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06/15/2022

    The CXCL12 protein is of exceptional quality, making it an ideal candidate to fulfill my experimental requirements.

    01/08/2022

      The manufacturer's commitment to providing excellent technical support is truly commendable, as they have proven to be readily available to assist in resolving any concerns or challenges I encountered while working with the protein.

      04/26/2021

        Its purity and integrity have consistently delivered reliable and robust results in my research.

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