Recombinant Mouse Cxcr2 Protein, His-tagged

• Cat.No.: Cxcr2-2168M
• Product Overview: Recombinant Mouse Cxcr2 Protein (Met1-Asp80) with a N-His tag was expressed in E. coli.

Specification

• Description: Enables chemokine receptor activity. Acts upstream of or within negative regulation of apoptotic process. Predicted to be located in several cellular components, including cell surface; mast cell granule; and mitotic spindle. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; epithelium; and heart. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; acute pyelonephritis; end stage renal disease; and urinary bladder cancer. Orthologous to human CXCR2 (C-X-C motif chemokine receptor 2).
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 12.9 kDa
  Accurate Molecular Mass: 15 kDa
• Protein length: Met1-Asp80
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Cxcr2 chemokine (C-X-C motif) receptor 2 [ Mus musculus (house mouse) ]
• Official Symbol: Cxcr2
• Synonyms: Cxcr2; chemokine (C-X-C motif) receptor 2; CD128; IL8RA; Il8rb; CDw128; Cmkar2; Gpcr16; IL-8Rh; IL-8rb; mIL-8RH; C-X-C chemokine receptor type 2
  CXC-R2
  CXCR-2
  GRO/MGSA receptor
  IL-8 receptor alpha chain
  IL-8R B
  chemokine (C-X-C) receptor 2
  high affinity interleukin-8 receptor B
  interleukin 8 receptor, beta
  interleukin-8 receptor type B
• Gene ID: 12765
• mRNA Refseq: NM_009909
• Protein Refseq: NP_034039
• UniProt ID: P35343