Recombinant Mouse Dnajb11 Protein, Myc/DDK-tagged

• Cat.No.: Dnajb11-2595M
• Product Overview: Purified recombinant protein of mouse full-length DnaJ heat shock protein family (Hsp40) member B11 (Dnajb11), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: As a co-chaperone for HSPA5 it is required for proper folding, trafficking or degradation of proteins. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. It is necessary for maturation and correct trafficking of PKD1.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 40.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 [ Mus musculus (house mouse) ]
• Official Symbol: Dnajb11
• Synonyms: DNAJB11; DnaJ (Hsp40) homolog, subfamily B, member 11; dnaJ homolog subfamily B member 11; APOBEC1-binding protein 2; ER-associated dnaJ protein 3; ER-associated Hsp40 co-chaperone; Dj9; ERdj3; ERj3p; ABBP-2; AL024055; 1810031F23Rik
• Gene ID: 67838
• mRNA Refseq: NM_001190805
• Protein Refseq: NP_001177734
• UniProt ID: Q99KV1