Recombinant Mouse Dnal1 Protein, MYC/DDK-tagged

• Cat.No.: Dnal1-272M
• Product Overview: Purified recombinant protein of full-length mouse dynein, axonemal, light chain 1 (Dnal1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency. Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme. Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry.
• Source: HEK293T
• Species: Mouse
• Tag: MYC/DDK
• Molecular Mass: 21.5 kDa
• Purity: >80%, as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dnal1 dynein, axonemal, light chain 1 [ Mus musculus (house mouse) ]
• Official Symbol: Dnal1
• Synonyms: Dnal1; dynein, axonemal, light chain 1; Dnalc1; AW121714; 1700010H15Rik; E330027P08Rik; dynein light chain 1, axonemal
• Gene ID: 105000
• mRNA Refseq: NM_028821
• Protein Refseq: NP_083097
• UniProt ID: Q05A62