Recombinant Mouse Dnase1 Protein, His-tagged

• Cat.No.: Dnase1-1358M
• Product Overview: Recombinant Mouse Dnase1 Protein (Leu23-Ile284) with N-His tag was expressed in E. coli.

Specification

• Description: Enables deoxyribonuclease I activity. Involved in several processes, including DNA catabolic process, endonucleolytic; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Predicted to be located in cytoplasmic vesicle and extracellular region. Predicted to be active in nucleus. Is expressed in jejunum; metanephros; and tongue. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to human DNASE1 (deoxyribonuclease 1).
• Source: E. coli
• Species: Mouse
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.4 kDa
  Accurate Molecular Mass: 33 kDa
• Protein length: Leu23-Ile284
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Dnase1 deoxyribonuclease I [ Mus musculus (house mouse) ]
• Official Symbol: Dnase1
• Synonyms: DNASE1; deoxyribonuclease I; deoxyribonuclease-1; Dnl1; DNaseI; AI788650; MGC144446; MGC144447
• Gene ID: 13419
• mRNA Refseq: NM_010061
• Protein Refseq: NP_034191
• UniProt ID: P49183