Recombinant Mouse Dnttip1 Protein, Myc/DDK-tagged

• Cat.No.: Dnttip1-2626M
• Product Overview: Purified recombinant protein of mouse full-length deoxynucleotidyltransferase, terminal, interacting protein 1 (Dnttip1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 36.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 [ Mus musculus (house mouse) ]
• Official Symbol: Dnttip1
• Synonyms: DNTTIP1; deoxynucleotidyltransferase, terminal, interacting protein 1; deoxynucleotidyltransferase terminal-interacting protein 1; tdIF1; tdT-interacting factor 1; terminal deoxynucleotidyltransferase-interacting factor 1; 6430706C13Rik
• Gene ID: 76233
• mRNA Refseq: NM_133763
• Protein Refseq: NP_598524
• UniProt ID: Q99LB0